논문투고-심사위원수정

대한임상미생물학회

   접수번호

  20180011

   접수일

  2018-04-23

   구분

  원저

   교신저자

  이혜경        (hk806194 : 이혜경)

   소속

  가톨릭의대 의정부 성모

   이메일

  hkl@catholic.ac.kr

   제목

  금속표면이 항생제 내성균주의 생육억제에 미치는 영향

   Running Title

  

   영문초록

  Background: The aim of this study is to analyze the comparative evaluation of bactericidal effect of copper, brass (copper 78%, tin 22%) and stainless steel against methicillin resistant Staphyloccoccus aureus (MRSA), vancomycin resistant enterococci (VRE) and Pseudomonas aeruginosa (PA).
Methods : These isolates (MRSA, VRE, PA) in this study were mixed wild type 3 strains isolated from patients of Uijeongbu St. Mary’s hospital in 2017. These strains showed multi-drug resistant patterns. The lyophilized strains were inoculated into and incubated for 24 hr in tryptic soy broth (TSB, Oxoid, England) at 35℃. The initial bacterial inoculum concentration was adjusted to 105 CFU/mL. 100 mL bacterial suspension were incubated on brass container (copper 78%, tin 22%) and copper container (above 99% purity), stainless steel container at 35℃ incubator. Until 9 days, viable counts of bacteria strains were measured.
Results : In this study, bactericidal effects of copper and brass on multidrug resistant (MDR) MRSA, VRE, PA were verified. The bactericidal effect of stainless steel was very weak than those of copper and brass. Bactericidal effect of PA was greater than those of MRSA and VRE.
Conclusion : To prevent hospital cross infection of MDR bacteria, further study of long duration is needed by application copper material at door-knob, faucet, and bed rail.

   Key Words

  copper, brass, bactericidal effect, multidrug resistant bacteria

   논문파일

1 . 표지(Title Page) A-20180011-1-00.hwp 13 Kbytes 2018-04-23
2 . 본문(Main Body) A-20180011-2-00.hwp 34 Kbytes 2018-04-23
3 . 이미지(Image File) A-20180011-3-00.pptx 159 Kbytes 2018-04-23
4 . 국문초록 A-20180011-4-00.hwp 15 Kbytes 2018-04-23
5 . 본문(Main Body) 1차 수정 A-20180011-2-01.hwp 40 Kbytes 2018-06-11
6 . 본문(Main Body) 2차 수정 A-20180011-2-02.hwp 73 Kbytes 2018-07-19
7 . 이미지(Image File) 2차 수정 A-20180011-3-02.pptx 76 Kbytes 2018-07-19
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