논문투고-심사위원수정

대한임상미생물학회

   접수번호

  20190001

   접수일

  2019-01-27

   구분

  종설

   교신저자

  신정환        (jhsmile7 : 신정환)

   소속

  인제대학교 의과대학

   이메일

  jhsmile@inje.ac.kr

   제목

  2015년 국내에서 분리된 살모넬라의 혈청형 및 항균제 감수성

   Running Title

  

   영문초록

  Background: Salmonella is an important pathogen that causes gastroenteritis and sepsis in humans. Recently, there have been reports of changes in the prevalent serotypes and an increase in antimicrobial drug resistance. This study aimed to investigate the distribution of Salmonella serotypes and to determine the antimicrobial susceptibility of various strains.
Methods: We collected 113 Salmonella isolates from 18 university hospitals in 2015. The serotypes were identified by Salmonella antisera O and H according to the Kauffman White scheme. Antimicrobial susceptibility tests for 12 antibiotics were performed using the disk diffusion method or E-test.
Results: We identified 22 serotypes. Serotype group B (44.2%) was the most common, followed by groups C (34.5%) and D (21.2%). Salmonella I4,[5],12:i:- (23.0%), S. Enteritidis (16.8%), and S. Typhimurium (12.4%) were the most common species. The resistance rates to ampicillin, chloramphenicol, ceftriaxone, and trimethoprim/sulfamethoxazole were 46.9%, 18.5%, 8.8%, and 5.3%, respectively. The intermediate resistance rate to ciprofloxacin was 29.2%. Six isolates were extended-spectrum β-lactamase (ESBL) producers, including 5 blaCTX-M-15 and 1 blaCTX-M-55.
Conclusion: There have been changes in the serotypes and antimicrobial resistance of Salmonella, with a high prevalence of CTX-M 15-positive strains in Korea. Continuous monitoring of Salmonella serotypes and antimicrobial resistance is required.

   Key Words

  Salmonella, Serotype, Antimicrobial resistance

   논문파일

1 . 표지(Title Page) A-20190001-1-00.docx 26 Kbytes 2019-01-27
2 . 본문(Main Body) A-20190001-2-00.docx 61 Kbytes 2019-01-27
3 . 국문초록 A-20190001-4-00.docx 24 Kbytes 2019-01-27
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